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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c37b9ca521249f66fd0cff8df627fcb0029fa90f9fbd981c48dd199f0d249da' 
  AND token = 'dE8BfG8M1xwAOzFyprjeRcC76b8Rg0+50mAlYI1yph8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}