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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe9e43ba7db295dca0eef0c9c1987f3ee61bd4e3cc70b560657589bd0f2b656' 
  AND token = '7upca7JuYP/gvZDj4VjtRJjQdbgDP4YfQ/ioXg+RMWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}