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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1dc5d5e1059a8624a4b04d511af702f979f4a492ee9f5451ca0b338c3c33322' 
  AND token = 'W2/AXnQ8W7xjJNms/p5zAbQqrEmaE1ndbIoA7LFdW1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}