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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c07caf64b1fce5a2f76fac76b0c06a5d01952c1c802bc2af81db4b01024c0957' 
  AND token = 'rBlHWHvxWHbB+IKN+/iYt5Y6Ee0w+SRw6ePcmvZub1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}