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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f114e2dd9f549ae522decd8fd91801ab06fbc0298974eec11d6fce3b45078f8d' 
  AND token = '+/K9dYjr+rtN5JWnfn1iktfrV0X6lPg8yDAxHNbYu9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}