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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1f6c241f0cca9bb74ce9568bda504ed5ed1c5b13f3377cf58c1d1fbf1fff39' 
  AND token = 'NLuGD+eB519WTS3al/aDrxO1DSLizVohnrBWW3UD9wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}