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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0452e75f325e04ab45df9c6cf91fec902edf73980a658d533ce9f089d62e1e' 
  AND token = 'Si6qgpZnCTH1xibk689RHToG9b11P48Os/M+ElxADjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}