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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878019e84d33d031475bfd2c587acbc59c0be82dc0b04eb4bfc55113e6e89900' 
  AND token = 'ALlKpGC5FBwoPqe19eFS6uym3lbiEfd/p+O0er9s5qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}