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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa19a2d51714640bed947cbf312591fe980664ce6494f426a6d45b876b7e1110' 
  AND token = 'XBw656p18lV8NBLLgoGE/WCbI5i9/wc+csmpV1hswEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}