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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4656919e2be63be2da27376a19b1f0c796b72c10467315830a1971447e190666' 
  AND token = '+Tk0T+5faBfqbKxJdl5zFW0aKEz1Lisk5+wK1GM7uwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}