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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bd645ef29bbac88aa468a78a63c3ef1c8f2869bc1061b63c4b074cda57e6d3' 
  AND token = 'kux8UT3PL8/g2TGopMkv+l5ltPri302zKQ+XdM8l30Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}