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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd385a1009478c910aad92e9c48e84ad3bfc2a1c0bb3476ff0d1f27ef47e4c0' 
  AND token = '6F5j3INg/lFAD2YAL76s4cGSTGdMZPDz3Y0LI3rJHN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}