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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9c5a2edf7706a5e73cb8391c5c61b68c1388e828531d4efc05e95d8187e4bc' 
  AND token = 'CU0Roy53+sM6pjWI7HrzfZQE9JrBtGeXX1U7S/KKjvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}