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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c163fd5c78e4bf9f8b87ef5060baf473b8d0ee9d7d8d149a4072d5ecf8ac396' 
  AND token = '3/kXEz2kxYjtL04cZfNBudzjsWKo3tykAYKbcTSvQIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}