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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e52420255d04aafe7a3f1e81167c40d98bce9e29b19b2a4fa7d008f8eb8404' 
  AND token = 'vNWhh1FsjO6OPYuPhmkEvIVll9WI+VkE13RMe4cEFr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}