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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380d9d316a677b2e2e0fbd076681a433b6b434bd78f9db083465933e86c81aee' 
  AND token = 'OhWBBCXzKSWHgBqDcD/t3x7LILtyM7ETakPW38HOyxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}