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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5f382152bdc4ce630c8597ed167c9e150fd940d3fcf6c95fabbf43440a66d5' 
  AND token = 'Toom5R20n/vEJOPmRzVT4l0CVIrsMLNkVB1N0BYJHjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}