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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8215683627021fd15b066ef1460d626500ee9869d5b0f2a1973bcc8e2fe1ede' 
  AND token = 'Ihq/Zd7hVMU356igOCgAO7VFBE9T//IGUBFWIwIAiIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}