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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c87343986901bbeddaf4db55b4ba3b2edd4498e09900732f21e0f18eb91f19e' 
  AND token = 'T+cwO6AmLd0Bk+JiJMnZvs3nuuFaKjRknCqHUEaZ5Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}