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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8dc7770946d5fa1c26a57e7144f53eee38471898a0787c75efab42131e25a40' 
  AND token = 'PGfdC8aF+Kv3xI00iEXVJl5G4IcLMkyQ0a1ls3DlMqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}