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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075182f2c06d9fbfc6a5eb053e9584a1703131b033b3fc9c7d9b1254fe2caf6d' 
  AND token = '3fUcqmfe5Y5s0T/nK2rUV2aMU+EoLu7DbETROQSkCwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}