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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16da00a0347758b1d931118dc4cde33fbe2d9306c250fed4f6fac38ae6ed36b1' 
  AND token = 'B3aimRJqD4AE/pN8rWWFdj1uCHySDnAGxrHfA30duYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}