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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc4a16700d2da1aa27c40617fac0fd279922f3941ba445d8f53d84294cdcb600' 
  AND token = 'yUj1sBAFfjWw0VugWf/dtodxkfzFXWANcB3dSJxkN3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}