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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def024e96be66de1d2d5f2f6ead8835948516b585cff825f8fee589db300e24d' 
  AND token = 'SJ76Z1ZEXOY0KEL2ixI0AQCOc6qKhJ8vmfcw583Agyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}