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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feaa4a1e05dfae00d91281a183ee7c68dc52541d1b3b60763b1ac8f21aa66f54' 
  AND token = 'Sm+D2vGupbFhv/sdDp6K+AAxyCpAG47YXy+cpZvLh/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}