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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7917ea72037d27fde760022c0e11816e4ec1277de69af0d62d86068d68e3cde9' 
  AND token = 'I7aV/C3KgTgnRxI134NGC0/VkXBKCYuqFT+Nvd4iGQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}