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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a050ad7ca2e02a065479009c81199f9881c61a2d68fc5aa3e226aed510912f9' 
  AND token = 'iQXJOI5PmF+ka1ynvLkCdyB/WR3t+XF6G0rvSQPq2OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}