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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa14a80e998812f90fed3317f40d188c8e11760da691cf3912f3bc9b4438b85d' 
  AND token = 'mKZyRck+aaVPg6yCUBpMGggLueXBTDPu2Jz2dz7UGRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}