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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3f6b8ace1b820b31312a605fb9e1f5a317c8330d91ea60e7fb1c86b7961cb4' 
  AND token = 'F8K9yhCbyXJKzbKmG2sl1pSCAyMOLUgbjL7mCL0Dndw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}