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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f225b4b008cb16438abc9693102264992413c5e972adc8c7badd10c810c6c77' 
  AND token = '1GYuFxbYcSFObgRx6zrNEJ4kPFePrc3nLnnuaBYfwz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}