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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0a06d6e714a84a5befed9bfdc594253db5c4e2a1de98dcc09e113590c02d73' 
  AND token = 'DBPhiUtPV3aTNY5VpI1zV4CaP6mJCV9P4dInOaGQ8EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}