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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0b9e1a38ce0c4e121cc68a23ef805a59d6021ecfab902c06a39a1c2d19a4c4' 
  AND token = '2n70Twxc2w2szLLOlNgUD0fZHQgWn4TH2ERnFyz1Mb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}