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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d33198c33e321d6811b513a6ebe43a7b1e63455dae7bacadcc4ac357de5564' 
  AND token = 'qKYrot2BrNHWlSYatxM/MbYfhLclmbXwLGd+TwG+pIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}