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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bc4842c43350afbbcb696e2dd7c9203de7ba10316107e45fce43e31c77a5b6' 
  AND token = '1G7Zni7qBsisZSPzJMT0eUzlr6/5j5z83D0obybJoW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}