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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65ade870c53690085fd134ec99806fd50fca7d35b2ced8b1ec2103f9fb37481' 
  AND token = 'SXpkVNiCN2lg1XH71h/2eCY97n6efXPCFGcLuHO+2VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}