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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2e1cfb6f7250faa52ce75f9e00200aa1467ce9c154c41ea1cf16f13c74607' 
  AND token = 'fNBlQnt10Os76lpcitfINBbmq1BjS2mXhz206m6rW9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}