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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5db765010519e8fcdb95c86ad2509b6a8959536e377123e90377c77202bbf75' 
  AND token = 'k7lpPgXxTYbwDSix10Jgx1gFWKDuEh6Bs4he2oNv8mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}