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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1145b929bca5b4d7375e9435748dcf9f7ced8a1e0b373f499debcb4b39ece647' 
  AND token = '6nheOEse3CVY/wugAHLm5rhsAKLbL3WmQNzm8FKwvIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}