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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6072814e9624ec4492b1022cdf228450b3914bbf5692a4d818cc9aedd235dcc' 
  AND token = 'LawfK8wOxe+qvSK86NZi6NAGj56ZaMNHQUDLkJ57mIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}