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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e318525d46c9ebc382a081bb0a0103c19dfd0c67d19dbced6bf780c334247d04' 
  AND token = '+V8o0Lj7hKhWZLDcnRDQfUVdvXQPgUPe18NFWq8izO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}