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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64849298e4bbb818a0ba04aa5092fec4bab6fcfd5e0deebe497d8594a00f8b4f' 
  AND token = 'dUr15pFZyRjnyF4suE3ErcX9Sw/IMKWsMZ1VAxW4kl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}