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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65cce540e6ce46b692d90f31744541f89697d0bad1428a7b052258f9153ce412' 
  AND token = 'jjoEWN6dnFn7Lj+/nVfsACnInprOQaQTKbESz3rbyEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}