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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab770b6b083c5171bf6535318abb23571525ac815a07a148b5b7e080bc7bb281' 
  AND token = 'OHWamHM4bm1HlFwQhexLgFVqPrtQ5PgCGUPz/SuGIBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}