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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d9cfa881099f002888ffe3a012a18dd6b2c761bfaf42892c3957b7f377a7df' 
  AND token = 'w6Tv6yDyhpEMeuZXMUbRa5i9/lU22rs6tpuDNQ2+FkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}