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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dff0fd2b441e83d6da9934a177491e0469a4e91dcd6e4616f434f51d764dce' 
  AND token = 'AuQZirV73BeaYUGcTHFXCJJ5CA2iQkqo/o3v9YgTXak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}