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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb0e13e949951e98a3f26dea1f5e260ed70a3bd358177da32567e03f1b2c4e4' 
  AND token = 'WCI0eUIrFxzBVQMQ59h8qph84PHc/hEgB0Sh4rVb9eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}