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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f238a8874684923c6eed1713b29f6f29659c9eb39b78b54076b9c2ec579899' 
  AND token = 'Hj4JVNHf1OoTNbwRViqleKpWe1nwvcY5frYAMtLsY5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}