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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d51a079ecb548bb3779da9c37daa3a7e31162768ad6bf3849bfba4bd89318c' 
  AND token = 'ka0Jg5gvOeJizeQbNsNYu1yuEfo8+mJ1rjkduMV/BOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}