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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6278fbd66e1b5b3db40c81a4ca841bf63ae1abf08cbcd90cb2059d2013069f92' 
  AND token = 'ocjMMEcthuoVhPDq9W1ZxLrmjda8/TRtov9Q0/9hr10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}