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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48059674aa7eca320ca013c99deb722f8efa4c5eb2a952301b0ec25443b662fd' 
  AND token = 'bYfLHkrNhSg1+VPoePM60A9NG9hW2OWcz6MA3IHgc0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}